Identification of 50-28-2

• Name:

• β-estradiol (Related Reference)

• EINECS:

• 200-023-8

• Synonyms:

• 1,3,5-estratriene-3,17beta-diol; 17beta-estradiol; 3,17beta-dihydroxy-1,3,5(10)-estratriene; dihydrofolliculin; ESTRADIOL

• InChI:

• InChI=1/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1

• This structure is also available as a 2d Mol file

• Risk Codes:

• R45

• Safety Statements:

• S53;S45

• Hazard Symbols:

• HazardClass:6.1
  

• MSDS infomation:

• β-estradiol (50-28-2).msds

• Appearance:

• white to off-white crystalline powder

• Molecular Weight:

• 272.38

• Density:

• 1.17g/cm³

• Boiling Point:

• 445.9°Cat760mmHg

• Melting Point:

• 173℃

• Flash Point:

• 209.6°C

• Storage Temperature:

• 2-8°C

• Refractive index:

• 1.599

• Solubility:

• practically insoluble <

• Biological Activity:

• Endogenous estrogen receptor (ER) agonist (K i values are 0.12 and 0.13 nM for ER α and ER β respectively). Also high affinity ligand at membrane estrogen GPR30 receptors.

• Stability:

• Stable. Incompatible with strong oxidizing agents.

• Usage:

• Potent mammalian estrogenic hormone produced by the ovary.