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PRODUCT
Home > Product > Estradiol
Chinese name:Estradiol
English name:Estradiol
CAS:57-91-0
EC NO:
Standard:
Packing:
Details:Estradiol 57-91-0

Identification of 57-91-0

  • Name:

  • Estra-1,3,5(10)-triene-3,17-diol,(17a)- (Related Reference)

  • EINECS:

  • 200-354-8

  • Synonyms:

  • 17a-Estradiol (8CI); 1,3,5-Estratriene-3,17a-diol; 13b-Methyl-1,3,5(10)-gonatriene-3,17a-diol; 17-Epiestradiol; 17a-Oestradiol; 3,17-Dihydroxyestratriene; 3,17a-Dihydroxyestra-1,3,5(10)-triene; 3,17a-Dihydroxyoestra-1,3,5(10)-triene; Alfatradiol; Epiestrol; Estra-1,3,5(10)-triene-3,17a-diol; NSC 20293; Oestra-1,3,5(10)-triene-3,17a-diol; a-Estradiol;

  • InChI:

  • InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17-,18+/m1/s1

  • This structure is also available as a 2d Mol file

Safety Data of 57-91-0Properties of 57-91-0
  • Appearance:

  • powder

  • Molecular Weight:

  • 272.38196

  • Density:

  • 1.17 g/cm3

  • Boiling Point:

  • 445.9 °C at 760 mmHg

  • Melting Point:

  • 176-180 °C(lit.)

  • Flash Point:

  • 209.6 °C

  • Storage Temperature:

  • 0-6°C

  • Refractive index:

  • 1.599

  • Solubility:

  • ethanol: 50 mg/mL, clear, colorless

  • Biological Activity:

  • Endogenous estrogen receptor ligand (K i values are 0.2 and 1.2 nM for ER α and ER β receptors respectively).

  • Usage:

  • Estradiol (known as α-Estradiol or 17 α-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Εstradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer’s disease and ischemic stroke.